Troponin-C is one of the three subunits that form the troponin complex of the thin filaments of striated muscle. Cardiac Tn-C is characterized by a molecular weight of ~18 kDa. It is expressed in heart and slow twitch skeletal muscle. Recombinant human cardiac Tn-C is purified from E. coli extracts using a combination of ion-exchange and affinity chromatography steps.
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